Technology Process of dimethyl (2S,3S)-2-(4-hydroxybenzyl)tartrate
There total 6 articles about dimethyl (2S,3S)-2-(4-hydroxybenzyl)tartrate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Amberlite IR-120B (H(+)-form);
In
methanol;
for 38h;
Heating;
DOI:10.1271/bbb.63.1934
- Guidance literature:
-
Multi-step reaction with 5 steps
1: tetrahydrofuran; diethyl ether / 0 °C
2: 0.32 g / benzene / 2 h / Heating
3: 93 percent / imidazole / dimethylformamide / 5 h / 20 °C
4: dihydroquinidine 1,4-phthalazinediyl diether; AD-mix-β; MeSO2NH2; K2OsO2(OH)4 / 2-methyl-propan-2-ol; H2O / 21 h / 4 °C
5: 99 percent / Amberlite IR-120B (H(+)-form) / methanol / 38 h / Heating
With
1H-imidazole; potassium dioxotetrahydroxoosmate(VI); methanesulfonamide; AD-mix-β; Amberlite IR-120B (H(+)-form); 1,4-bis(9-O-dihydroquinidine)phthalazine;
In
tetrahydrofuran; methanol; diethyl ether; water; N,N-dimethyl-formamide; tert-butyl alcohol; benzene;
1: Esterification / 2: Wittig reaction / 3: silylation / 4: dihydroxylation / 5: desilylation;
DOI:10.1271/bbb.63.1934
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 93 percent / imidazole / dimethylformamide / 5 h / 20 °C
2: dihydroquinidine 1,4-phthalazinediyl diether; AD-mix-β; MeSO2NH2; K2OsO2(OH)4 / 2-methyl-propan-2-ol; H2O / 21 h / 4 °C
3: 99 percent / Amberlite IR-120B (H(+)-form) / methanol / 38 h / Heating
With
1H-imidazole; potassium dioxotetrahydroxoosmate(VI); methanesulfonamide; AD-mix-β; Amberlite IR-120B (H(+)-form); 1,4-bis(9-O-dihydroquinidine)phthalazine;
In
methanol; water; N,N-dimethyl-formamide; tert-butyl alcohol;
1: silylation / 2: dihydroxylation / 3: desilylation;
DOI:10.1271/bbb.63.1934