N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-[2-(ethylamino)ethyl]glycinamide hydrochloride

Base Information

• Chemical Name: N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-[2-(ethylamino)ethyl]glycinamide hydrochloride
• CAS No.: 1190884-33-3
• Molecular Formula: C₂₇H₃₄FN₇O₃*ClH
• Molecular Weight: 560.071

Synonyms:N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-[2-(ethylamino)ethyl]glycinamide hydrochloride

Chemical Property of N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-[2-(ethylamino)ethyl]glycinamide hydrochloride

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Technology Process of N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-[2-(ethylamino)ethyl]glycinamide hydrochloride

There total 2 articles about N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-[2-(ethylamino)ethyl]glycinamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N2-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N2-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N1-[2-(ethylamino)ethyl]glycinamide (1190889-68-9) → N2-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N2-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N1-[2-(ethylamino)ethyl]glycinamide hydrochloride (1190884-33-3)

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 0 - 30 ℃;

Reference yield:

hydrochloric acid ethyl acetate → N2-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N2-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N1-[2-(ethylamino)ethyl]glycinamide hydrochloride (1190884-33-3)

Guidance literature:

With aqueous ammonia; trifluoroacetic acid; In ethanol; dichloromethane; N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-{2-[(tert-butoxycarbonyl)(ethyl)amino]ethyl}glycinamide; ethyl acetate;

upstream raw materials:

N₂-{2-[(5-fluoro-1,3-dihydro-2H-isoindol-2-yl)(methyl)amino]-2-oxoethyl}-N₂-[2-methyl-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N₁-[2-(ethylamino)ethyl]glycinamide

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