5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide

Base Information

• Chemical Name: 5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide
• CAS No.: 1586765-15-2
• Molecular Formula: C₂₁H₂₀ClN₅O
• Molecular Weight: 393.876

Synonyms:5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide

Chemical Property of 5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide

There total 2 articles about 5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C11H10ClN3O (88958-20-7) + 5-chlorotryptamine hydrochloride (942-26-7,55747-73-4) → 5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide (1586765-15-2)

Guidance literature:

With potassium carbonate; In dichloromethane; 1,2-dichloro-ethane; at 25 ℃; for 12h;

DOI:10.1134/S1070428014020225

Reference yield:

5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid (210159-05-0) → 5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide (1586765-15-2)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride

2: potassium carbonate / 1,2-dichloro-ethane; dichloromethane / 12 h / 25 °C

With thionyl chloride; potassium carbonate; In dichloromethane; 1,2-dichloro-ethane;

DOI:10.1134/S1070428014020225

Reference yield: 81.0%

5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide (1586765-15-2) → 1-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-6-chloro-4,9-dihydro-3H-β-carboline (1586765-21-0)

Guidance literature:

With phosphorus pentoxide; trichlorophosphate; In toluene; at 110 ℃; for 12h;

DOI:10.1134/S1070428014020225

upstream raw materials:

C₁₁H₁₀ClN₃O

5-chlorotryptamine hydrochloride

5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylic acid

Downstream raw materials:

1-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-6-chloro-4,9-dihydro-3H-β-carboline

1-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-6-chloro-9H-β-carboline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1586765-15-2 5-methyl-1-(4-methylphenyl)-N-[2-(5-chloro-1H-indol-3-yl)ethyl]-1H-1,2,3-triazole-4-carboxamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send