(S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide

Base Information

Chemical Name:(S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide
CAS No.:934178-99-1
Molecular Formula:C₁₅H₁₄ClF₃N₄O
Molecular Weight:358.751
Hs Code.:

Synonyms:(S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide

Suppliers and Price of (S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide

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Technology Process of (S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide

There total 1 articles about (S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26032-72-4
2,4-dichloro-6-phenyl-pyrimidine

: 916201-86-0
(S)-2-amino-N-(2,2,2-trifluoroethyl)propanamide

: 934178-99-1
(S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In isopropyl alcohol; at 80 ℃;

Reference yield:

: 934178-99-1
(S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide

: 934178-97-9
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-(p-toluenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine

: (S)-2-(6-phenyl-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl)pyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide

Guidance literature:: (S)-2-(2-chloro-6-phenylpyrimidin-4-ylamino)-N-(2,2,2-trifluoroethyl)propanamide; 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-7-(p-toluenesulfonyl)-7H-pyrrolo[2,3-d]pyrimidine; With sodium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,4-dioxane; at 80 ℃;

With lithium hydroxide; In 1,4-dioxane; water; at 60 ℃; for 1h;