(E)-1-(4-Difluoromethoxy-3-methoxy-phenyl)-3-(6-trifluoromethyl-pyridin-3-yl)-propenone

Base Information

Chemical Name:(E)-1-(4-Difluoromethoxy-3-methoxy-phenyl)-3-(6-trifluoromethyl-pyridin-3-yl)-propenone
CAS No.:1056446-82-2
Molecular Formula:C₁₇H₁₂F₅NO₃
Molecular Weight:373.279
Hs Code.:

Synonyms:(E)-1-(4-Difluoromethoxy-3-methoxy-phenyl)-3-(6-trifluoromethyl-pyridin-3-yl)-propenone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-1-(4-Difluoromethoxy-3-methoxy-phenyl)-3-(6-trifluoromethyl-pyridin-3-yl)-propenone

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Technology Process of (E)-1-(4-Difluoromethoxy-3-methoxy-phenyl)-3-(6-trifluoromethyl-pyridin-3-yl)-propenone

There total 1 articles about (E)-1-(4-Difluoromethoxy-3-methoxy-phenyl)-3-(6-trifluoromethyl-pyridin-3-yl)-propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 773874-12-7
4-difluoromethoxy-3-methoxy-benzoic acid methyl ester

: 756-79-6
dimethyl methane phosphonate

: 386704-12-7,872626-76-1
6-(trifluoromethyl)pyridine-3-carbaldehyde

: 1056446-82-2
(E)-1-(4-Difluoromethoxy-3-methoxy-phenyl)-3-(6-trifluoromethyl-pyridin-3-yl)-propenone

Guidance literature:: dimethyl methane phosphonate; With n-butyllithium; In tetrahydrofuran; hexane; at -65 ℃; for 0.5h;

4-difluoromethoxy-3-methoxy-benzoic acid methyl ester; In tetrahydrofuran; hexane; at -70 - 0 ℃; for 0.25h;

6-(trifluoromethyl)pyridine-3-carbaldehyde; With hydrogenchloride; caesium carbonate; more than 3 stages;