C₂₂H₂₁NO₂Se

Base Information

• Chemical Name: C₂₂H₂₁NO₂Se
• CAS No.: 944453-12-7
• Molecular Formula: C₂₂H₂₁NO₂Se
• Molecular Weight: 410.374
• Mol file: 944453-12-7.mol

Synonyms:C₂₂H₂₁NO₂Se

Chemical Property of C₂₂H₂₁NO₂Se

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₁NO₂Se

There total 3 articles about C₂₂H₂₁NO₂Se which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C16H17NO2 (944453-11-6) + Phenylselenyl bromide (34837-55-3) → C22H21NO2Se (944453-12-7)

Guidance literature:

With copper(l) iodide; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.tetlet.2007.04.115

Reference yield:

phthalimide (136918-14-4,85-41-6) → C22H21NO2Se (944453-12-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / DIAD; Ph₃P / tetrahydrofuran / 0 - 20 °C

2: 85 percent / CuI / dimethylformamide / 20 °C

With copper(l) iodide; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; 1: Mitsunobu reaction;

DOI:10.1016/j.tetlet.2007.04.115

Reference yield:

1-octyn-3-ol (32556-71-1,37911-28-7) → C22H21NO2Se (944453-12-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / DIAD; Ph₃P / tetrahydrofuran / 0 - 20 °C

2: 85 percent / CuI / dimethylformamide / 20 °C

With copper(l) iodide; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; N,N-dimethyl-formamide; 1: Mitsunobu reaction;

DOI:10.1016/j.tetlet.2007.04.115

upstream raw materials:

C₁₆H₁₇NO₂

Phenylselenyl bromide

phthalimide

1-octyn-3-ol

Downstream raw materials:

C₂₂H₂₃NO₃Se