(3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol

Base Information

• Chemical Name: (3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol
• CAS No.: 1323371-50-1
• Molecular Formula: C₆₉H₇₇NO₁₄
• Molecular Weight: 1144.37
• Mol file: 1323371-50-1.mol

Synonyms:(3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol

Chemical Property of (3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol

There total 1 articles about (3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + C64H69NO12 → (3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol (1323371-50-1)

Guidance literature:

In toluene; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1016/j.tetlet.2011.06.005

Reference yield:

(3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol (1323371-50-1) → C67H75NO13

Guidance literature:

With methanol; sodium methylate; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.tetlet.2011.06.005

Reference yield:

(3,4-di-O-benzyl-6-O-acetyl-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol (1323371-50-1) → (3,4-di-O-benzyl-6-azido-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-2,3,4,5-tetra-O-benzyl-L-myo-inositol (1323371-60-3)

Guidance literature:

Multi-step reaction with 4 steps

1: methanol; sodium methylate / dichloromethane / 2 h / 20 °C / Inert atmosphere

2: pyridine / 3 h / 0 - 20 °C / Inert atmosphere; Molecular sieve

3: sodium azide / N,N-dimethyl-formamide / 3 h / 110 - 120 °C / Inert atmosphere

4: water; 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

With pyridine; methanol; sodium azide; water; sodium methylate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2011.06.005

upstream raw materials:

di-tert-butyl dicarbonate

Downstream raw materials:

(3,4-di-O-benzyl-6-azido-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-1-O-p-methoxybenzyl-2,3,4,5-tetra-O-benzyl-L-myo-inositol

(3,4-di-O-benzyl-6-azido-2-N-(tert-butyloxycarbonyl)amino-2-deoxy-α-D-glucopyranosyl)-(1->6)-2,3,4,5-tetra-O-benzyl-L-myo-inositol