methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate

Base Information

• Chemical Name: methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate
• CAS No.: 1374986-80-7
• Molecular Formula: C₂₅H₃₁NO₇S
• Molecular Weight: 489.59

Synonyms:methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate

Chemical Property of methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate

There total 2 articles about methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

methyl 3-hydroxy-5-((3-methylbut-2-en-1-yl)oxy)benzoate (955886-88-1) + (cis)-4-((4-bromophenyl)sulfonyl)-2,6-dimethylmorpholine (1374986-84-1) → methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate (1374986-80-7)

Guidance literature:

With 2,2,6,6-tetramethylheptane-3,5-dione; caesium carbonate; copper(I) bromide; In 1-methyl-pyrrolidin-2-one; at 110 ℃; Inert atmosphere;

DOI:10.1016/j.bmc.2012.03.008

Reference yield:

cis-2,6-dimethylmorpholine (141-91-3,6485-45-6,6485-55-8) → methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate (1374986-80-7)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 4 h

2: 2,2,6,6-tetramethylheptane-3,5-dione; caesium carbonate; copper(I) bromide / 1-methyl-pyrrolidin-2-one / 110 °C / Inert atmosphere

With pyridine; 2,2,6,6-tetramethylheptane-3,5-dione; caesium carbonate; copper(I) bromide; In 1-methyl-pyrrolidin-2-one; dichloromethane;

DOI:10.1016/j.bmc.2012.03.008

Reference yield: 100.0%

methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate (1374986-80-7) → C24H29NO7S (1393120-64-3)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; water; for 2h; Reflux;

DOI:10.1016/j.bmc.2012.03.008

upstream raw materials:

methyl 3-hydroxy-5-((3-methylbut-2-en-1-yl)oxy)benzoate

(cis)-4-((4-bromophenyl)sulfonyl)-2,6-dimethylmorpholine

cis-2,6-dimethylmorpholine

Downstream raw materials:

C₂₄H₂₉NO₇S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1374986-80-7 methyl 3-(4-(((2S,6R)-2,6-dimethylmorpholino)sulfonyl)phenoxy)-5-((3-methylbut-2-en-1-yl)oxy)benzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send