N-phenylpyrazine-2-carboxamide

Base Information

Chemical Name:N-phenylpyrazine-2-carboxamide
CAS No.:34067-83-9
Molecular Formula:C11H9 N3 O
Molecular Weight:199.212
Hs Code.:
NSC Number:131185
UNII:JNB7EV5YWW
DSSTox Substance ID:DTXSID80187666
Nikkaji Number:J1.495.659J
Wikidata:Q83059375

Synonyms:Pyrazinecarboxamide,N-phenyl- (9CI); Pyrazinecarboxanilide (7CI,8CI); 2-Pyrazinecarboxanilide; NSC131185

Suppliers and Price of N-phenylpyrazine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N-phenylpyrazine-2-carboxamide

Chemical Property:

Vapor Pressure:0.00669mmHg at 25°C
Boiling Point:270.8°Cat760mmHg
Flash Point:117.6°C
Density:1.287g/cm³
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:199.074561919
Heavy Atom Count:15
Complexity:214

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=O)C2=NC=CN=C2

Technology Process of N-phenylpyrazine-2-carboxamide

There total 16 articles about N-phenylpyrazine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 4744-50-7
2,3-pyrazinedicarboxylic anhydride

: 62-53-3
aniline

: 34067-83-9
N-(phenyl)pyrazine-2-carboxamide

Guidance literature:: In toluene; for 12h; Inert atmosphere; Reflux;
DOI:10.1021/ol402200x

Reference yield: 90.0%

: 6164-79-0
methyl pyrazine-2-carboxylate

: 62-53-3
aniline

: 34067-83-9
N-(phenyl)pyrazine-2-carboxamide

Guidance literature:: With sodium t-butanolate; In neat (no solvent); at 20 ℃; for 1h; Inert atmosphere; Schlenk technique; Green chemistry;
DOI:10.1039/d1gc00720c

Reference yield: 86.0%

: 98-97-5
2-pyrazylcarboxylic acid

: 62-53-3
aniline

: 34067-83-9
N-(phenyl)pyrazine-2-carboxamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;
DOI:10.1021/ol500464x