2,3,4',5',6',7'-hexa-O-benzyl-4,5-O-benzyllidenevalidoxylamine B

Base Information

• Chemical Name: 2,3,4',5',6',7'-hexa-O-benzyl-4,5-O-benzyllidenevalidoxylamine B
• CAS No.: 117320-21-5
• Molecular Formula: C₆₃H₆₅NO₉
• Molecular Weight: 980.21
• Mol file: 117320-21-5.mol

Synonyms:2,3,4',5',6',7'-hexa-O-benzyl-4,5-O-benzyllidenevalidoxylamine B

Chemical Property of 2,3,4',5',6',7'-hexa-O-benzyl-4,5-O-benzyllidenevalidoxylamine B

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4',5',6',7'-hexa-O-benzyl-4,5-O-benzyllidenevalidoxylamine B

There total 12 articles about 2,3,4',5',6',7'-hexa-O-benzyl-4,5-O-benzyllidenevalidoxylamine B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1D-(1,3,6/2)-6-amino-4-benzyloxymethyl-1,2,3-tri-O-benzyltrihydroxycyclohex-4-ene (114779-32-7) + (1R,2S,5R,7R,8R,9R,10R)-8,9-dibenzyloxy-5-phenyl-4,6,11-trioxatricyclo<8.1.0.02.7>undecane (114779-35-0) → (1S,3S,6S,7R,8S,9S,10R)-9,10-dibenzyloxy-7-<(1S)-(1,4,6/5)-4,5,6-tribenzyloxy-3-benzyloxymethylcyclohex-2enylamino>-8-hygroxy-3-phenyl-2,4-dioxabicyclo<4.4.0>decane (118968-10-8,121521-17-3) + 2,3,4',5',6',7'-hexa-O-benzyl-4,5-O-benzyllidenevalidoxylamine B (117320-21-5)

Guidance literature:

In isopropyl alcohol; at 120 ℃;

DOI:10.1246/cl.1988.889

Reference yield: 75.0%

1D-(1,3,6/2)-6-amino-4-benzyloxymethyl-1,2,3-tri-O-benzyltrihydroxycyclohex-4-ene (114779-32-7) + (1aR,2S,3S,3aR,5R,7aS,7bR)-2,3-Bis-benzyloxy-5-phenyl-hexahydro-1,4,6-trioxa-cyclopropa[a]naphthalene (114779-35-0,148347-66-4) → (1S,3S,6S,7R,8S,9S,10R)-9,10-dibenzyloxy-7-<(1S)-(1,4,6/5)-4,5,6-tribenzyloxy-3-benzyloxymethylcyclohex-2enylamino>-8-hygroxy-3-phenyl-2,4-dioxabicyclo<4.4.0>decane (118968-10-8,121521-17-3) + 2,3,4',5',6',7'-hexa-O-benzyl-4,5-O-benzyllidenevalidoxylamine B (117320-21-5)

Guidance literature:

In isopropyl alcohol; at 120 ℃; for 110h;

Reference yield: 75.0%

1D-(1,3,6/2)-6-amino-4-benzyloxymethyl-1,2,3-tri-O-benzyltrihydroxycyclohex-4-ene (114779-32-7) + (1R,2S,5R,7R,8R,9R,10R)-8,9-dibenzyloxy-5-phenyl-4,6,11-trioxatricyclo<8.1.0.02.7>undecane (114779-35-0) → (1S,3S,6S,7R,8S,9S,10R)-9,10-dibenzyloxy-7-<(1S)-(1,4,6/5)-4,5,6-tribenzyloxy-3-benzyloxymethylcyclohex-2-enylamino>-8-hydroxy-3-phenyl-2,4-dioxabicyclo<4.4.0>-decane (118968-10-8) + 2,3,4',5',6',7'-hexa-O-benzyl-4,7-O-benzylidenevalidoxylamine B (117320-21-5)

Guidance literature:

In isopropyl alcohol; at 120 ℃; for 110h; sealed tube;

DOI:10.1039/P19880002675

upstream raw materials:

1D-(1,3,6/2)-6-amino-4-benzyloxymethyl-1,2,3-tri-O-benzyltrihydroxycyclohex-4-ene

(1aR,2S,3S,3aR,5R,7aS,7bR)-2,3-Bis-benzyloxy-5-phenyl-hexahydro-1,4,6-trioxa-cyclopropa[a]naphthalene

(1R,2S,5R,7R,8R,9R,10R)-8,9-dibenzyloxy-5-phenyl-4,6,11-trioxatricyclo<8.1.0.0^2.7>undecane

benzaldehyde dimethyl acetal

Downstream raw materials:

validoxylamine B

4,7-di-O-acetyl-2,3,6,4',5',6',7'-hepta-O-benzylvalidoxylamine B

7-O-acetyl-2,3,6,4',5',6',7'-hepta-O-benzylvalidoxylamine B

2,3,6,4',5',6',7'-hepta-O-benzylvalidoxylamine B