2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile

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Chemical Name:2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile
CAS No.:945995-75-5
Molecular Formula:C₂₂H₂₁N₃O₃
Molecular Weight:375.427
Hs Code.:

Synonyms:2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile

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Chemical Property of 2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile

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Technology Process of 2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile

There total 1 articles about 2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 824-94-2
p-methoxybenzyl chloride

: 945995-75-5
2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile

Guidance literature:: 2-{[(5-ethyl-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile; With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2.16667h;

p-methoxybenzyl chloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2.66667h;

Reference yield: 65.0%

: 945995-75-5
2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile

: 945995-76-6
6-{[2-(aminomethyl)benzyl]oxy}-5-ethyl-3-(4-methoxybenzyl)pyrimidin-4(3H)-one

Guidance literature:: 2-{[(5-ethyl-1-(4-methoxybenzyl)-6-oxo-1,6-dihydropyrimidin-4-yl)oxy]methyl}benzonitrile; With sodium tetrahydroborate; cobalt(II) chloride; In methanol; at 0 - 20 ℃; for 0.75h;

With hydrogenchloride; methanol; water;

With sodium hydrogencarbonate; In methanol; water; pH=> 9;