5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine

Base Information

Chemical Name:5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine
CAS No.:118632-06-7
Molecular Formula:C₁₇H₁₀ClF₃N₄OS
Molecular Weight:410.807
Hs Code.:

Synonyms:5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine

Chemical Property:

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Technology Process of 5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine

There total 3 articles about 5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 118632-00-1
3-<(2'-aminophenyl)thio>-5-(4'-chlorophenyl)-1,2,4-triazine

: 407-25-0
trifluoroacetic anhydride

: 118632-06-7
5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine

Guidance literature:: In diethyl ether; for 0.75h;
DOI:10.1021/jo00267a045

Reference yield:

: 105783-78-6
5-(4'-chlorophenyl)-3-(methylsulfonyl)-1,2,4-triazine

: 118632-06-7
5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / tetrahydrofuran / 6 h

2: 100 percent / diethyl ether / 0.75 h

In tetrahydrofuran; diethyl ether;
DOI:10.1021/jo00267a045

Reference yield:

: 137-07-5
2-amino-benzenethiol

: 118632-06-7
5-(4'-chlorophenyl)-3-<(2'-trifluoroacetamidophenyl)thio>-1,2,4-triazine

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / tetrahydrofuran / 6 h

2: 100 percent / diethyl ether / 0.75 h

In tetrahydrofuran; diethyl ether;
DOI:10.1021/jo00267a045