2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate

Base Information

• Chemical Name: 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate
• CAS No.: 21823-89-2
• Molecular Formula: C₂₇H₂₁NO₈
• Molecular Weight: 487.466
• Mol file: 21823-89-2.mol

Synonyms:2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate

Chemical Property of 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate

There total 3 articles about 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (6974-32-9) → 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate (21823-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl (gas) / diethyl ether / 72 h / -5 °C

2: toluene / 3 h / Heating

With hydrogenchloride; In diethyl ether; toluene;

DOI:10.1021/jo00342a020

Reference yield:

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose (67525-66-0) → 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate (21823-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / 1,2-dichloro-ethane / 1)saturated at 0 deg C, 2h 2)room temp., overnight

2: toluene / 24 h / Ambient temperature

With hydrogenchloride; In 1,2-dichloro-ethane; toluene;

Reference yield:

→ 2,3,5-tri-O-benzoyl-β-D-ribosyl isocyanate (21823-89-2)

Guidance literature:

DOI:10.1021/jo00828a062 DOI:10.1016/S0040-4020(01)92397-X

upstream raw materials:

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

Downstream raw materials:

tri-O-benzoyl-1-(5-chloro-3-oxo-3H-[1,2,4]thiadiazol-2-yl)-β-D-1-deoxy-ribofuranose

C₃₁H₃₀N₄O₁₀

4-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)semicarbazide

N-(2,2-diethoxyethyl)-N'-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)urea