1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside

Base Information

Chemical Name:1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside
CAS No.:1422376-20-2
Molecular Formula:C₁₈H₂₇NO₄
Molecular Weight:321.417
Hs Code.:

Synonyms:1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside

Suppliers and Price of 1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside

There total 8 articles about 1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₈H₂₅NO₄

: 1422376-20-2
1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside

Guidance literature:: With sodium tetrahydroborate; In methanol; for 0.166667h;
DOI:10.1016/j.tet.2012.12.049

Reference yield:

: 55174-92-0
1,2-O-isopropylidene-5-O-2,2-dimethylpropanoyl-α-D-erythro-pent-3-ulofuranose

: 1422376-20-2
1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydroxylamine hydrochloride; sodium hydrogencarbonate / ethanol / 3.5 h / Reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C / Reflux

3.1: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / tetrahydrofuran / 0.25 h

3.2: 48 h

4.1: titanium(IV) isopropylate / 1 h / 20 °C

5.1: sodium tetrahydroborate / methanol / 0.17 h

With titanium(IV) isopropylate; sodium tetrahydroborate; lithium aluminium tetrahydride; hydroxylamine hydrochloride; tetra(n-butyl)ammonium hydrogensulfate; sodium hydrogencarbonate; sodium hydroxide; In tetrahydrofuran; methanol; ethanol;
DOI:10.1016/j.tet.2012.12.049

Reference yield:

: 55174-95-3
1,2-O-isopropylidene-5-O-trimethylacetyl-α-D-erythro-pent-3-ulofuranose oxime

: 1422376-20-2
1,2-O-isopropylidene-3-benzylamino-3-deoxy-5-O-n-propyl-α-D-ribofuranoside

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 1.5 h / 0 °C / Reflux

2.1: sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate / tetrahydrofuran / 0.25 h

2.2: 48 h

3.1: titanium(IV) isopropylate / 1 h / 20 °C

4.1: sodium tetrahydroborate / methanol / 0.17 h

With titanium(IV) isopropylate; sodium tetrahydroborate; lithium aluminium tetrahydride; tetra(n-butyl)ammonium hydrogensulfate; sodium hydroxide; In tetrahydrofuran; methanol;
DOI:10.1016/j.tet.2012.12.049