1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one

Base Information

• Chemical Name: 1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one
• CAS No.: 152770-37-1
• Molecular Formula: C₁₅H₁₆N₆O₇
• Molecular Weight: 392.328
• Mol file: 152770-37-1.mol

Synonyms:1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one

Chemical Property of 1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one

There total 2 articles about 1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

4-nitrobenzenediazonium tetrafluoroborate (456-27-9) + C9H12N3O5(1-)*K(1+) (132658-08-3) → 1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one (152770-37-1)

Guidance literature:

In acetone; at 20 ℃; for 18h;

DOI:10.1007/BF00531663

Reference yield:

4-nitrobenzenediazonium tetrafluoroborate (456-27-9) + 5-Nitro-5H-2-acetonyl-4,6-dimethoxy-2,5-dihydropyrimidine (132658-20-9) → 1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one (152770-37-1)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction; 1.) hexane, THF, -78 deg C, 15 min, 2.) hexane, THF, -78 deg C, 2 h;

DOI:10.1007/BF00531663

Reference yield: 91.0%

1-[4,6-Dimethoxy-5-nitro-5-(4-nitro-phenylazo)-2,5-dihydro-pyrimidin-2-yl]-propan-2-one (152770-37-1) → potassium salt of 2-acetylmethine-5-(4-nitrophenylazo)-4,6-dimethoxypyrimidine

Guidance literature:

With potassium hydroxide; In methanol; for 3h;

DOI:10.1007/BF00531663

upstream raw materials:

4-nitrobenzenediazonium tetrafluoroborate

5-Nitro-5H-2-acetonyl-4,6-dimethoxy-2,5-dihydropyrimidine

C₉H₁₂N₃O₅^(1-)*K⁽¹⁺⁾

Downstream raw materials:

1-[4,6-Dimethoxy-5-(4-nitro-phenylazo)-pyrimidin-2-yl]-propan-2-one