1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine

Base Information

• Chemical Name: 1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine
• CAS No.: 502636-32-0
• Molecular Formula: C₂₉H₄₃NO₂
• Molecular Weight: 437.666

Synonyms:1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine

Chemical Property of 1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine

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Technology Process of 1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine

There total 3 articles about 1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-pyrrolidinocyclopent-1-ene (7148-07-4) → 1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine (502636-32-0)

Guidance literature:

In tetrahydrofuran; at 60 ℃; for 6h;

DOI:10.1021/ja0278077

Reference yield:

1-pyrrolidinocyclopent-1-ene (7148-07-4) → 1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine (502636-32-0)

Guidance literature:

In tetrahydrofuran; at 60 ℃; for 6h;

DOI:10.1021/ja0278077

Reference yield:

1-pyrrolidinocyclopent-1-ene (7148-07-4) → 1-[(1R,2aS,2bR,4aR,4bR)-2a-((1R,2S,5R)-2-Isopropyl-5-methyl-cyclohexyloxy)-1-(4-methoxy-phenyl)-hexahydro-cyclopropa[cd]pentalen-4b-yl]-pyrrolidine (502636-32-0)

Guidance literature:

In tetrahydrofuran; at 60 ℃; for 6h;

DOI:10.1021/ja002905i

upstream raw materials:

1-pyrrolidinocyclopent-1-ene

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