Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt

Base Information

• Chemical Name: Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt
• CAS No.: 132400-97-6
• Molecular Formula: C₈₄H₁₁₈N₁₄O₁₉S₂
• Molecular Weight: 1692.08
• Mol file: 132400-97-6.mol

Synonyms:Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt

Chemical Property of Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt

There total 1 articles about Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

H-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt<*>TFA + Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-N2H3 (132400-91-0) → Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt (132400-97-6)

Guidance literature:

With hydrogenchloride; triethylamine; isopentyl nitrite; Yield given. Multistep reaction; 1.) DMF, - 50 deg C, 10 min 2.) DMF, stirring, -4 deg C, 6 d;

DOI:10.1246/bcsj.63.3467

Reference yield: 93.0%

Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt (132400-97-6) → H-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt<*>TFA (132400-99-8)

Guidance literature:

With trifluoroacetic acid; at 0 ℃; for 0.5h;

DOI:10.1246/bcsj.63.3467

upstream raw materials:

Boc-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-N₂H₃

Downstream raw materials:

H-Cys(Acm)-Orn(Z)-Leu-D-Phe-Pro-Val-Orn(Z)-Cys(Acm)-D-Phe-Pro-OEt<*>TFA