N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester

Base Information

Chemical Name:N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester
CAS No.:857502-21-7
Molecular Formula:C₂₈H₄₅NO₁₀Sn
Molecular Weight:674.376
Hs Code.:

Synonyms:N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester

Suppliers and Price of N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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American Custom Chemicals Corporation
N-TERT-BUTOXYCARBONYL-3,4-DI-TERT-BUTOXYCARBONYLOXY-6-(TRIMETHYLSTANNYL)-L-PHENYLALANINE METHYL ESTER 95.00%
5MG
$ 503.38

Total 0 raw suppliers

Chemical Property of N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester

Chemical Property:

Purity/Quality:: N-TERT-BUTOXYCARBONYL-3,4-DI-TERT-BUTOXYCARBONYLOXY-6-(TRIMETHYLSTANNYL)-L-PHENYLALANINE METHYL ESTER 95.00% ^*data from reagent suppliers

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Technology Process of N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester

There total 4 articles about N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1213203-66-7
iodo-DOPA

: 661-69-8
hexamethyldistannane

: 857502-21-7
N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester

Guidance literature:: With lithium chloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 23 - 100 ℃;

Reference yield: 37.0%

: 1403599-91-6
N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-bromo-L-phenylalaninemethyl ester

: 661-69-8
hexamethyldistannane

: 857502-21-7
N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride; In 1,4-dioxane; at 100 ℃; for 5h;
DOI:10.1021/ja3084797

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 857502-21-7
N-(tert-butoxycarbonyl)-3,4-di(tert-butoxycarbonyloxy)-6-trimethylstannyl-L-phenylalaninemethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / toluene / 9 h / 80 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium chloride / 1,4-dioxane / 5 h / 100 °C

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; lithium chloride; In 1,4-dioxane; toluene;
DOI:10.1021/ja3084797