2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole

Base Information

Chemical Name:2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole
CAS No.:1541187-90-9
Molecular Formula:C₂₂H₂₂N₄O₃S
Molecular Weight:422.508
Hs Code.:

Synonyms:2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole

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Chemical Property of 2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole

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Technology Process of 2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole

There total 5 articles about 2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1541189-88-1
C₂₈H₃₆N₄O₄SSi

: 1541187-90-9
2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; for 2h;

Reference yield:

: 80945-86-4
6-bromo-2-chloro-benzothiazole

: 1541187-90-9
2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole

Guidance literature:: Multi-step reaction with 3 steps

1: potassium tert-butylate / N,N-dimethyl-formamide / 0.17 h / 100 °C / Microwave irradiation

2: copper(l) iodide; 2-Picolinic acid; potassium phosphate / dimethyl sulfoxide / 78 h / 140 °C / Inert atmosphere

3: hydrogenchloride / methanol; 1,4-dioxane / 2 h

With 2-Picolinic acid; hydrogenchloride; potassium phosphate; copper(l) iodide; potassium tert-butylate; In 1,4-dioxane; methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 622-40-2
2-(morpholin-4-yl)ethanol

: 1541187-90-9
2-(2-morpholin-4-ylethoxy)-6-[4-(1H-pyrazol-3-yl)phenoxy]benzothiazole

Guidance literature:: Multi-step reaction with 3 steps

1: potassium tert-butylate / N,N-dimethyl-formamide / 0.17 h / 100 °C / Microwave irradiation

2: copper(l) iodide; 2-Picolinic acid; potassium phosphate / dimethyl sulfoxide / 78 h / 140 °C / Inert atmosphere

3: hydrogenchloride / methanol; 1,4-dioxane / 2 h

With 2-Picolinic acid; hydrogenchloride; potassium phosphate; copper(l) iodide; potassium tert-butylate; In 1,4-dioxane; methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;