4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene

Base Information

• Chemical Name: 4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene
• CAS No.: 1291101-58-0
• Molecular Formula: C₃₅H₃₇BN₂
• Molecular Weight: 496.503
• Mol file: 1291101-58-0.mol

Synonyms:4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene

Chemical Property of 4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene

There total 7 articles about 4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

bromobenzene (108-86-1,52753-63-6) + 2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-phenyl-4-bora-3a,4a-diaza-s-indecene → 4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene (1291101-58-0)

Guidance literature:

bromobenzene; With iodine; magnesium; In diethyl ether; Reflux;

2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8-phenyl-4-bora-3a,4a-diaza-s-indecene; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/acs.joc.1c01254

Reference yield: 7.0%

2,6-diethyl-4,4-difluoro-1,3,5,7-tetramethyl-8H-4-bora-3a,4a-diaza-s-indacene + phenyllithium (591-51-5) → 1,3,5,7-tetramethyl-2,6-diethyl-8-H-4,4'-diphenyl-bora-3a,4a-diaza-s-indacene (1219485-15-0) + 4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene (1291101-58-0)

Guidance literature:

In diethyl ether; dibutyl ether; at 20 - 25 ℃; for 18h; Inert atmosphere;

DOI:10.3987/COM-10-12099

Reference yield:

2,4-dimethyl-3-ethyl-pyrrole (517-22-6) → 4,4-diphenyl-1,3,5,7-tetramethyl-2,6-diethyl-8-phenyl-4-bora-3a,4a-diaza-s-indacene (1291101-58-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: dichloromethane / 0.17 h / 20 °C

1.2: 0.5 h / 20 °C

2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / 20 °C

2.2: 20 °C

3.1: magnesium; iodine / diethyl ether / Reflux

3.2: 1 h / 20 °C

With iodine; magnesium; N-ethyl-N,N-diisopropylamine; In diethyl ether; dichloromethane;

DOI:10.1021/acs.joc.1c01254

upstream raw materials:

phenyllithium

2,4,8,10-tetramethyl-3,9-diethyldipyrrolyl-5,7-methene

2,4,8,10-tetramethyl-3,9-diethyldipyrrolyl-5,7-methene hydrobromide

benzaldehyde