Technology Process of 6,7-dichloro-2-methyl-2-phenyl-5-(1H-tetrazol-5-ylmethoxy)-indan-1-one
There total 9 articles about 6,7-dichloro-2-methyl-2-phenyl-5-(1H-tetrazol-5-ylmethoxy)-indan-1-one which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
ammonium chloride;
In
N-methyl-acetamide;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: aluminium trichloride / dichloromethane
2: bromine; sodium hydrogensulfite / acetic acid
3: lithium bromide / N,N-dimethyl-formamide
4: (2S)-N-methyl-1-phenylpropan-2-amine hydrate; sulfuric acid
5: potassium tert-butylate / water; tert-butyl alcohol
6: pyridine hydrochloride
7: potassium iodide; potassium carbonate / acetone
8: ammonium chloride / N-methyl-acetamide
With
lithium bromide; potassium iodide; ammonium chloride; potassium tert-butylate; bromine; pyridine hydrochloride; potassium carbonate; sodium hydrogensulfite;
aluminium trichloride;
In
N-methyl-acetamide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane; sulfuric acid; water; acetic acid; N,N-dimethyl-formamide; acetone; tert-butyl alcohol;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: bromine; sodium hydrogensulfite / acetic acid
2: lithium bromide / N,N-dimethyl-formamide
3: (2S)-N-methyl-1-phenylpropan-2-amine hydrate; sulfuric acid
4: potassium tert-butylate / water; tert-butyl alcohol
5: pyridine hydrochloride
6: potassium iodide; potassium carbonate / acetone
7: ammonium chloride / N-methyl-acetamide
With
lithium bromide; potassium iodide; ammonium chloride; potassium tert-butylate; bromine; pyridine hydrochloride; potassium carbonate; sodium hydrogensulfite;
In
N-methyl-acetamide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; sulfuric acid; water; acetic acid; N,N-dimethyl-formamide; acetone; tert-butyl alcohol;