1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane

Base Information

• Chemical Name: 1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane
• CAS No.: 1403588-82-8
• Molecular Formula: C₅₃H₆₀O₇Si
• Molecular Weight: 837.141
• Mol file: 1403588-82-8.mol

Synonyms:1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane

Chemical Property of 1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane

There total 1 articles about 1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C37H42O7 + tert-butylchlorodiphenylsilane (58479-61-1) → 1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane (1403588-82-8) + 1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2S)-ol-3-tert-butyldiphenylsilyloxypropane (1403588-83-9)

Guidance literature:

With pyridine; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c2ob26078f

Reference yield: 57.0%

1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane (1403588-82-8) → C46H52O6Si (1403588-84-0)

Guidance literature:

With pyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 ℃; for 0.25h; Inert atmosphere;

DOI:10.1039/c2ob26078f

Reference yield:

1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2R)-ol-3-tert-butyldiphenylsilyloxypropane (1403588-82-8) + p-toluenesulfonyl chloride (98-59-9) → C60H66O9SSi

Guidance literature:

With pyridine; In dichloromethane; at 0 - 100 ℃; for 36h; Inert atmosphere;

DOI:10.1039/c2ob26078f

upstream raw materials:

tert-butylchlorodiphenylsilane

Downstream raw materials:

1-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-(2S)-azido-3-propanol

(S)-methyl 2-azido-3-((2S,3S,4R,5S,6R)-3,4,5-tris(benzyloxy)-6-((benzyloxy)methyl) tetrahydro-2H-pyran-2-yl)-propanoate

methyl 3C-β-(2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl)-N-tert-butoxycarbonyl-L-alanine

C₄₆H₅₂O₆Si