2-hexahydroazepin-2-ylacetophenone

Base Information

• Chemical Name: 2-hexahydroazepin-2-ylacetophenone
• CAS No.: 132970-96-8
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.311
• Mol file: 132970-96-8.mol

Synonyms:2-hexahydroazepin-2-ylacetophenone

Chemical Property of 2-hexahydroazepin-2-ylacetophenone

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-hexahydroazepin-2-ylacetophenone

There total 3 articles about 2-hexahydroazepin-2-ylacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

3-oxo-3-phenylpropionic acid (614-20-0) + hexane-1,6-diamine dihydrochloride (6055-52-3) → 2-hexahydroazepin-2-ylacetophenone (132970-96-8)

Guidance literature:

In water; at 25 ℃; for 24h; catalase, pea seedling diamine oxidase, pH 7.7;

Reference yield:

tetrahydroazepine (2214-81-5) + 3-oxo-3-phenylpropionic acid (614-20-0) → 2-hexahydroazepin-2-ylacetophenone (132970-96-8)

Guidance literature:

Yield given;

DOI:10.1016/S0040-4039(00)97204-6

Reference yield:

1,6-Hexanediamine (124-09-4) → 2-hexahydroazepin-2-ylacetophenone (132970-96-8)

Guidance literature:

Multi-step reaction with 2 steps

1: O₂, H₂O / 30 °C / pH 7, diamine oxidase (DAO), catalase

With water; oxygen;

DOI:10.1016/S0040-4039(00)97204-6

upstream raw materials:

tetrahydroazepine

3-oxo-3-phenylpropionic acid

hexane-1,6-diamine dihydrochloride

1,6-Hexanediamine

Refernces

• 1、 Cragg, John E.,Herbert, Richard B.,Kgaphola, Mashupye M.. "PEA-SEEDLING DIAMINE OXIDASE: APPLICATIONS IN SYNTHESIS AND EVIDENCE RELATING TO ITS MECHANISM OF ACTION". . p. 6907 - 6910. Retrieved 2007/10/02.