Boc-D-Homoallylglycine

Base Information

• Chemical Name: Boc-D-Homoallylglycine
• CAS No.: 219819-76-8
• Molecular Formula: C₁₁H₁₉NO₄
• Molecular Weight: 229.276
• DSSTox Substance ID: DTXSID901184834
• Nikkaji Number: J1.010.885C
• Mol file: 219819-76-8.mol

Synonyms:219819-76-8;Boc-D-Homoallylglycine;(R)-2-((tert-Butoxycarbonyl)amino)hex-5-enoic acid;(2R)-2-[(2-methylpropan-2-yl)oxycarbonylamino]hex-5-enoic acid;(2r)-2-(boc-amino)-5-hexenoic acid;(R)-N-Boc-2-(3'-butenyl)glycine;Boc-(2R)-2-Amino-5-Hexenoic Acid;DTXSID901184834;BS-51987;F76895;(2R)-2-(tert-Butoxycarbonylamino)-5-hexenoic acid;(2R)-2-[(TERT-BUTOXYCARBONYL)AMINO]-5-HEXENOIC ACID;(2R)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-5-hexenoic acid

Chemical Property of Boc-D-Homoallylglycine

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 229.13140809
• Heavy Atom Count: 16
• Complexity: 268

Purity/Quality:

98%,99%, ^*data from raw suppliers

(2R)-2-[(tert-Butoxycarbonyl)amino]-5-hexenoic acid AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NC(CCC=C)C(=O)O
• Isomeric SMILES: CC(C)(C)OC(=O)N[C@H](CCC=C)C(=O)O

Technology Process of Boc-D-Homoallylglycine

There total 1 articles about Boc-D-Homoallylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclopropylmethyl iodide (33574-02-6) + di-tert-butyl dicarbonate (24424-99-5) + 2-amino-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N-methylacetamide (170115-96-5) → pseudoephedrine (90-82-4,7009-81-6,90-83-5,6912-63-6) + (R)-2-tert-Butoxycarbonylamino-hex-5-enoic acid (219819-76-8) + (R)-2-((tert-butoxycarbonyl)amino)-3-cyclopropylpropanoic acid (89483-08-9)

Guidance literature:

With sodium hydroxide; sodium hydrogencarbonate; lithium chloride; lithium diisopropyl amide; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/ja00137a034

Reference yield:

(R)-2-tert-Butoxycarbonylamino-hex-5-enoic acid (219819-76-8) → C33H50N4O7 (1445578-65-3)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine; benzotriazol-1-ol; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / 18 h / 20 °C

2: lithium hydroxide / methanol; tetrahydrofuran; water / 2 h / 20 °C

3: triethylamine; benzotriazol-1-ol; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / 18 h / 20 °C / Cooling

With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; lithium hydroxide; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;

DOI:10.1021/jo4001492

Reference yield:

(R)-2-tert-Butoxycarbonylamino-hex-5-enoic acid (219819-76-8) → C28H42N4O5*C2HF3O2

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine; benzotriazol-1-ol; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / 18 h / 20 °C

2: lithium hydroxide / methanol; tetrahydrofuran; water / 2 h / 20 °C

3: triethylamine; benzotriazol-1-ol; dicyclohexyl-carbodiimide / N,N-dimethyl-formamide / 18 h / 20 °C / Cooling

4: 3 h / 0 °C

With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; lithium hydroxide; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;

DOI:10.1021/jo4001492

upstream raw materials:

cyclopropylmethyl iodide

di-tert-butyl dicarbonate

2-amino-N-[(1S,2S)-2-hydroxy-1-methyl-2-phenylethyl]-N-methylacetamide

Downstream raw materials:

C₃₃H₅₀N₄O₇

(+)-(3R,9R,14aS)-9-benzyl-3-(but-3-enyl)-6,6-dimethyldecahydropyrrolo[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10-tetraone

C₃₇H₅₈N₄O₇S₂Si

C₃₄H₅₄N₄O₆Si

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 219819-76-8 (R)-N-Boc-2-(3'-butenyl)glycine

Send

Send

Metric Ton KG G Pound L ML

Send

Send