6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine

Base Information

• Chemical Name: 6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine
• CAS No.: 1185886-17-2
• Molecular Formula: C₃₉H₄₀Cl₂N₄O₂
• Molecular Weight: 667.678
• Mol file: 1185886-17-2.mol

Synonyms:6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine

Chemical Property of 6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine

There total 1 articles about 6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptane-1-amine (681211-35-8) + C19H14ClNO3*ClH (1185886-14-9) → 6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine (1185886-17-2)

Guidance literature:

C₁₉H₁₄ClNO₃*ClH; With chloroformic acid ethyl ester; triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

N¹-(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)heptane-1,7-diamine; In dichloromethane; at 20 ℃;

DOI:10.1021/jm900859q

Reference yield:

6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine (1185886-17-2) → 6-chloro-9-{{7-[5-(4-chlorophenyl)-3,4-dihydro-2H-pyrano[3,2-c]quinoline-9-carboxamido]heptyl}amino}-1,2,3,4-tetrahydroacridine dihydrochloride

Guidance literature:

With hydrogenchloride; In methanol; dichloromethane;

DOI:10.1021/jm900859q

upstream raw materials:

7-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]heptane-1-amine

C₁₉H₁₄ClNO₃*ClH