5-(4'-chlorophenyl)-2,4-pentadienol

Base Information

• Chemical Name: 5-(4'-chlorophenyl)-2,4-pentadienol
• CAS No.: 27394-83-8
• Molecular Formula: C₁₁H₉ClO
• Molecular Weight: 192.645
• Mol file: 27394-83-8.mol

Synonyms:5-(4'-chlorophenyl)-2,4-pentadienol

Chemical Property of 5-(4'-chlorophenyl)-2,4-pentadienol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4'-chlorophenyl)-2,4-pentadienol

There total 3 articles about 5-(4'-chlorophenyl)-2,4-pentadienol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

C11H9ClO (1047660-78-5) → 5-(4'-chlorophenyl)-2,4-pentadienol (27394-83-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; triphenyl-arsane; acetic acid; In toluene; at 100 ℃; Inert atmosphere;

DOI:10.1002/ejoc.201001082

Reference yield: 75.0%

4-chlorobenzaldehyde (104-88-1) + (E)-(4-Oxo-2-butenyl)phosphonsaeure-diethylester (110905-37-8) → 5-(4'-chlorophenyl)-2,4-pentadienol (27394-83-8)

Guidance literature:

With cyclohexylamine; lithium diisopropyl amide; In tetrahydrofuran; at 0 - 25 ℃; for 17h;

DOI:10.1021/jo00306a006

Reference yield: 71.0%

→ 5-(4'-chlorophenyl)-2,4-pentadienol (27394-83-8)

Guidance literature:

With dicarbonyl(acetylacotonato)rhodium(I); hydrogen; 2,2'-bis((bis(5-methoxy-1H-indol-1-yl)phosphaneyl)oxy)-1,1'-biphenyl; In toluene; at 25 ℃; for 8h; under 7500.75 Torr;

upstream raw materials:

4-chlorobenzaldehyde

(E)-(4-Oxo-2-butenyl)phosphonsaeure-diethylester

C₁₁H₉ClO

Refernces

• 1、 Shao, Li-Xiong,Li, Jia,Wang, Bao-Yu,Shi, Min. "Palladium-catalyzed reactions of 3-substituted methylenecyclopropanes". supporting information; experimental part. p. 6448 - 6453. Retrieved 2011/02/21.