1,2-O-isopropylidene-5-O-toluene-p-sulphonyl-β-D-arabinofuranose

Base Information

• Chemical Name: 1,2-O-isopropylidene-5-O-toluene-p-sulphonyl-β-D-arabinofuranose
• CAS No.: 40429-51-4
• Molecular Formula: C₁₅H₂₀O₇S
• Molecular Weight: 344.386
• Mol file: 40429-51-4.mol

Synonyms:1,2-O-isopropylidene-5-O-toluene-p-sulphonyl-β-D-arabinofuranose

Chemical Property of 1,2-O-isopropylidene-5-O-toluene-p-sulphonyl-β-D-arabinofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-O-isopropylidene-5-O-toluene-p-sulphonyl-β-D-arabinofuranose

There total 16 articles about 1,2-O-isopropylidene-5-O-toluene-p-sulphonyl-β-D-arabinofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,2-O-isopropylidene-α-D-xylose (20031-21-4) + p-toluenesulfonyl chloride (98-59-9) → 1,2-di-O-isopropylidene-5-O-tosyl-D-xylofuranose (6893-65-8,20513-95-5,20513-96-6,34981-06-1,40429-51-4,110349-61-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; Inert atmosphere;

DOI:10.1016/j.carres.2009.03.025

Reference yield: 93.0%

tosylimidazolide + 1,2-O-isopropylidene-α-D-xylose (20031-21-4) → 1,2-di-O-isopropylidene-5-O-tosyl-D-xylofuranose (6893-65-8,20513-95-5,20513-96-6,34981-06-1,40429-51-4,110349-61-6)

Guidance literature:

With 1-methyl-1H-imidazole; methyl trifluoromethanesulfonate; In tetrahydrofuran; at 0 ℃; for 6h;

DOI:10.1021/jo051644y

Reference yield: 82.0%

1,2-O-isopropylidene-α-D-xylose (20031-21-4) + p-toluenesulfonyl chloride (98-59-9) → 2,2-dimethyl-6-(4-methylphenylsulfonyloxymethyl)-5-(4-methylphenylsulfonyloxymethyl)-(3aR,5R,6S,6aR)-perhydrofuro[2,3-d][1,3]dioxole (4119-18-0,7010-99-3,7061-63-4,55073-85-3) + 1,2-di-O-isopropylidene-5-O-tosyl-D-xylofuranose (6893-65-8,20513-95-5,20513-96-6,34981-06-1,40429-51-4,110349-61-6)

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1016/S0040-4020(03)01068-8

upstream raw materials:

1,2-O-isopropylidene-α-D-xylose

p-toluenesulfonyl chloride

D-xylose

1,2:3,5-di-O-isopropylidene-D-xylofuranose

Downstream raw materials:

3-O-acetyl-1,2-O-isopropylidene-5-O-p-toluenesulfonyl-α-D-xylofuranose

3-O-benzoyl-1,2-O-isopropylidene-5-O-p-toluenesulfonyl-α-D-xylofuranose

1,2-O-isopropylidene-3-O-methyl-5-O-p-tolylsulfonyl-α-D-xylofuranose

5-amino-5-deoxy-1,2-O-isopropylidene-a-D-xylofuranose