(E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate

Base Information

• Chemical Name: (E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate
• CAS No.: 1166391-14-5
• Molecular Formula: C₁₅H₁₈O₄
• Molecular Weight: 262.306
• Mol file: 1166391-14-5.mol

Synonyms:(E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate

Chemical Property of (E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate

Chemical Property:

Purity/Quality:

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Technology Process of (E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate

There total 1 articles about (E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3,4-dihydro-2H-pyran (110-87-2) + methyl 4-hydroxycinnamate (3943-97-3) → (E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate (1166391-14-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃;

DOI:10.1080/00397910802542036

Reference yield: 80.0%

(E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate (1166391-14-5) → (E)-3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)prop-2-en-1-ol (99522-58-4)

Guidance literature:

(E)-methyl 3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl) acrylate; With lithium aluminium tetrahydride; In diethyl ether; at 0 - 20 ℃;

With water; In diethyl ether; at 0 ℃;

DOI:10.1080/00397910802542036

upstream raw materials:

3,4-dihydro-2H-pyran

methyl 4-hydroxycinnamate

Downstream raw materials:

(E)-3-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)prop-2-en-1-ol