1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene

Base Information

• Chemical Name: 1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene
• CAS No.: 288581-13-5
• Molecular Formula: C₅₄H₆₀N₆
• Molecular Weight: 793.111
• Mol file: 288581-13-5.mol

Synonyms:1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene

Chemical Property of 1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene

There total 2 articles about 1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',7',7a'-tetrahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene → 1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene (288581-13-5)

Guidance literature:

With hydrogen; platinum(IV) oxide; In benzene; at 20 ℃; for 24h;

DOI:10.1021/ja0003369

Reference yield:

cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) + 1,3,5-tris{3'-(4',4'-dimethyl-5'-phenyl)-[4H]-pyrazole}benzene (288581-17-9) → 1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene (288581-13-5)

Guidance literature:

cyclopenta-1,3-diene; 1,3,5-tris{3'-(4',4'-dimethyl-5'-phenyl)-[4H]-pyrazole}benzene; With trifluoroacetic acid; In dichloromethane; at -20 - 5 ℃; for 72h;

With hydrogen; platinum(IV) oxide; In benzene; at 20 ℃; for 24h; Further stages.;

DOI:10.1021/jo0012795

Reference yield: 94.0%

1,3,5-tris-1'-{(1'α,4'α,4a'α,7a'α)-4',4a',5',6',7',7a'-hexahydro-8',8'-dimethyl-4'-phenyl-1',4'-methano-1H-cyclopenta[d]pyrazidine}benzene (288581-13-5) → 1,3,5-tris-2'-(3',3'-dimethyl-4'-phenyltricyclo[3.3.0.02',4']octanyl)benzene

Guidance literature:

In benzene-d6; for 0.166667h; Irradiation;

DOI:10.1021/jo0012795

upstream raw materials:

cyclopenta-1,3-diene

1,3,5-tris{3'-(4',4'-dimethyl-5'-phenyl)-[4H]-pyrazole}benzene