Technology Process of C12H16O
There total 5 articles about C12H16O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C13H18O2;
With
diisobutylaluminium hydride;
In
toluene;
at -78 - 20 ℃;
for 1.5h;
Inert atmosphere;
With
hydrogenchloride;
In
water;
at 20 ℃;
for 2.5h;
Inert atmosphere;
DOI:10.1039/c3ob27491h
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: potassium carbonate / methanol / 2 h / Inert atmosphere
3.1: potassium tert-butylate / dimethyl sulfoxide / 0.67 h / Inert atmosphere
4.1: diisobutylaluminium hydride / toluene / 1.5 h / -78 - 20 °C / Inert atmosphere
4.2: 2.5 h / 20 °C / Inert atmosphere
With
n-butyllithium; potassium tert-butylate; diisobutylaluminium hydride; potassium carbonate; diisopropylamine;
In
tetrahydrofuran; methanol; hexane; dimethyl sulfoxide; toluene;
DOI:10.1039/c3ob27491h
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / methanol / 2 h / Inert atmosphere
2.1: potassium tert-butylate / dimethyl sulfoxide / 0.67 h / Inert atmosphere
3.1: diisobutylaluminium hydride / toluene / 1.5 h / -78 - 20 °C / Inert atmosphere
3.2: 2.5 h / 20 °C / Inert atmosphere
With
potassium tert-butylate; diisobutylaluminium hydride; potassium carbonate;
In
methanol; dimethyl sulfoxide; toluene;
DOI:10.1039/c3ob27491h
