C₄₄H₄₃BBr₂F₂N₂S₄

Base Information

• Chemical Name: C₄₄H₄₃BBr₂F₂N₂S₄
• CAS No.: 1588866-96-9
• Molecular Formula: C₄₄H₄₃BBr₂F₂N₂S₄
• Molecular Weight: 936.719
• Mol file: 1588866-96-9.mol

Synonyms:C₄₄H₄₃BBr₂F₂N₂S₄

Chemical Property of C₄₄H₄₃BBr₂F₂N₂S₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₄₃BBr₂F₂N₂S₄

There total 8 articles about C₄₄H₄₃BBr₂F₂N₂S₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C44H45BF2N2S4 (1588866-86-7) → C44H43BBr2F2N2S4 (1588866-96-9)

Guidance literature:

With N-Bromosuccinimide; In chloroform; at 0 ℃; for 3h; Darkness;

DOI:10.1021/ol500572t

Reference yield:

5-(4-methylphenyl)dipyrromethane (147804-55-5) → C44H43BBr2F2N2S4 (1588866-96-9)

Guidance literature:

Multi-step reaction with 5 steps

1: chloranil / dichloromethane / 2 h / 20 °C / Inert atmosphere

2: triethylamine; chloranil; boron trifluoride diethyl etherate / dichloromethane / 2 h / 20 °C / Inert atmosphere

3: N-Bromosuccinimide / dichloromethane; N,N-dimethyl-formamide / 3 h / 25 °C / Darkness

4: tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; caesium carbonate; tri-tert-butyl phosphine / tetrahydrofuran / 12 h / 40 °C

5: N-Bromosuccinimide / chloroform / 3 h / 0 °C / Darkness

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; N-Bromosuccinimide; tri-tert-butyl phosphine; boron trifluoride diethyl etherate; chloranil; caesium carbonate; triethylamine; In tetrahydrofuran; dichloromethane; chloroform; N,N-dimethyl-formamide; 4: |Suzuki Coupling;

DOI:10.1021/ol500572t

Reference yield:

5-(4-methylphenyl)dipyrrin (1606994-41-5) → C44H43BBr2F2N2S4 (1588866-96-9)

Guidance literature:

Multi-step reaction with 4 steps

1: triethylamine; chloranil; boron trifluoride diethyl etherate / dichloromethane / 2 h / 20 °C / Inert atmosphere

2: N-Bromosuccinimide / dichloromethane; N,N-dimethyl-formamide / 3 h / 25 °C / Darkness

3: tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; caesium carbonate; tri-tert-butyl phosphine / tetrahydrofuran / 12 h / 40 °C

4: N-Bromosuccinimide / chloroform / 3 h / 0 °C / Darkness

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; N-Bromosuccinimide; tri-tert-butyl phosphine; boron trifluoride diethyl etherate; chloranil; caesium carbonate; triethylamine; In tetrahydrofuran; dichloromethane; chloroform; N,N-dimethyl-formamide; 3: |Suzuki Coupling;

DOI:10.1021/ol500572t

upstream raw materials:

3-bromo-5’-n-hexyl-2,2’-bithiophene

4-methyl-benzaldehyde

5-(4-methylphenyl)dipyrromethane

5-(4-methylphenyl)dipyrrin

Downstream raw materials:

C₄₄H₃₉BBr₂F₂N₂S₄

Refernces