(R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate

Base Information

Chemical Name:(R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate
CAS No.:1416820-93-3
Molecular Formula:C₂₂H₂₇NO₅
Molecular Weight:385.46
Hs Code.:

Synonyms:(R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate

Chemical Property:

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Technology Process of (R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate

There total 3 articles about (R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 222555-05-7
ethyl (2R)-2-ethoxy-3-(4-hydroxyphenyl)propanoate

: 1359827-42-1
2-bromo-1-(5-ethylpyridin-2-yl)ethanone hydrobromide

: 1416820-93-3
(R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 373368-68-4
(R)-3-[4-(benzyloxy)phenyl]-2-hydroxypropanoic acid

: 1416820-93-3
(R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium hydroxide / dimethyl sulfoxide / 20 °C

2: hydrogen / palladium 10% on activated carbon / ethanol / 4 h / 1034.32 - 1551.49 Torr

3: caesium carbonate / N,N-dimethyl-formamide / 20 °C

With hydrogen; caesium carbonate; potassium hydroxide; palladium 10% on activated carbon; In ethanol; dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 847268-21-7
ethyl (2R)-3-[4-(benzyloxy)phenyl]-2-ethoxypropanoate

: 1416820-93-3
(R)-ethyl 2-ethoxy-3-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)phenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / palladium 10% on activated carbon / ethanol / 4 h / 1034.32 - 1551.49 Torr

2: caesium carbonate / N,N-dimethyl-formamide / 20 °C

With hydrogen; caesium carbonate; palladium 10% on activated carbon; In ethanol; N,N-dimethyl-formamide;