5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol

Base Information

Chemical Name:5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol
CAS No.:1083429-83-7
Molecular Formula:C₂₁H₂₀N₄O₃
Molecular Weight:376.415
Hs Code.:

Synonyms:5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol

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Chemical Property of 5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol

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Technology Process of 5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol

There total 1 articles about 5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1083429-83-7
5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol

Guidance literature:

Reference yield:

: 1083429-83-7
5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol

: 1083429-82-6
3-(6-chloro-pyridin-3-yl)-6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazine

Guidance literature:: With trichlorophosphate; for 3h; Heating / reflux; Neat (no solvent);

Reference yield:

: 1083429-83-7
5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-pyridin-2-ol

: 1083428-81-2
5-[6-(4-ethoxy-3-methoxy-phenyl)-2-methyl-imidazo[1,2-b]pyridazin-3-yl]-[2,3']bipyridinyl-6'-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / 3 h / Heating / reflux; Neat (no solvent)

2: potassium carbonate / bis-triphenylphosphine-palladium(II) chloride / water; N,N-dimethyl-formamide / 2 h / 105 °C / Microwave irradiation

With potassium carbonate; trichlorophosphate; bis-triphenylphosphine-palladium(II) chloride; In water; N,N-dimethyl-formamide;