Technology Process of 2-(5-Fluoro-1H-benzoimidazole-2-sulfinylmethyl)-phenylamine
There total 6 articles about 2-(5-Fluoro-1H-benzoimidazole-2-sulfinylmethyl)-phenylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 82.4 percent / K2CO3 / CHCl3 / 1.) 4 h, 2.) RT, overnight
2: SOCl2 / benzene / 1 h / Heating
3: NaOH / H2O; ethanol / 2 h / Ambient temperature
4: 30percent HBr-AcOH / 3 h / Ambient temperature
5: 87.1 percent / m-chloroperbenzoic acid / CHCl3; methanol / 0.5 h / -5 °C
With
sodium hydroxide; thionyl chloride; hydrogen bromide; potassium carbonate; acetic acid; 3-chloro-benzenecarboperoxoic acid;
In
methanol; ethanol; chloroform; water; benzene;
DOI:10.1016/0223-5234(91)90024-H
- Guidance literature:
-
Multi-step reaction with 3 steps
1: NaOH / H2O; ethanol / 2 h / Ambient temperature
2: 30percent HBr-AcOH / 3 h / Ambient temperature
3: 87.1 percent / m-chloroperbenzoic acid / CHCl3; methanol / 0.5 h / -5 °C
With
sodium hydroxide; hydrogen bromide; acetic acid; 3-chloro-benzenecarboperoxoic acid;
In
methanol; ethanol; chloroform; water;
DOI:10.1016/0223-5234(91)90024-H
