17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone

Base Information

Chemical Name:17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone
CAS No.:95716-74-8
Molecular Formula:C₂₃H₂₈O₅
Molecular Weight:384.472
Hs Code.:

Synonyms:17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone

Suppliers and Price of 17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 6 raw suppliers

Chemical Property of 17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

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Technology Process of 17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone

There total 1 articles about 17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95716-71-5
Δ⁹⁽¹¹⁾-canrenone

: 95716-74-8
17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone

Guidance literature:: Multi-step reaction with 5 steps

1.1: 77.7 percent / boron trifluoride diethyl etherate; EtOH; isopropanol / acetonitrile / 24 h / -18.4 °C

2.1: potassium acetate; dibromantin / acetone; H₂O / -10 °C

3.1: aq. HCl / CH₂Cl₂ / 2.5 h / 20 °C

4.1: O₃/O₂ / CH₂Cl₂; propan-2-ol / 0.17 h / -55 °C

4.2: dimethylsilfide / CH₂Cl₂; propan-2-ol / 0.83 h / 20 °C

5.1: 0.865 mg / H₂O₂; KHCO₃ / H₂O; methanol / 16 h / 20 °C

With hydrogenchloride; 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; ethanol; boron trifluoride diethyl etherate; dihydrogen peroxide; oxygen; potassium acetate; potassium hydrogencarbonate; ozone; isopropyl alcohol; In methanol; dichloromethane; water; isopropyl alcohol; acetone; acetonitrile; 5.1: Baeyer-Villiger oxidation;
DOI:10.1021/ol060503v

Reference yield:

: 95716-74-8
17β-hydroxypregna-4,9(11)-dien-3-one-7α,21-dicarboxylic acid γ-lactone

: 107724-20-9
eplerenone

Guidance literature:: Multi-step reaction with 2 steps

1: 2.7 g / CH₂Cl₂; diethyl ether / 0.17 h

2: 71.6 percent / aq. H₂O₂, (CCl₃CO)2O / CH₂Cl₂ / 1.5 h / below 4 deg C

With dihydrogen peroxide; trichloroacetic acid anhydride; In diethyl ether; dichloromethane;
DOI:10.1002/hlca.19970800220