4-[3-ethoxycarbonyl-2-hydroxy-3-(phenylseleno)butyl]-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester

Base Information

• Chemical Name: 4-[3-ethoxycarbonyl-2-hydroxy-3-(phenylseleno)butyl]-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester
• CAS No.: 1007229-51-7
• Molecular Formula: C₂₃H₃₄O₇Se
• Molecular Weight: 501.479
• Mol file: 1007229-51-7.mol

Synonyms:4-[3-ethoxycarbonyl-2-hydroxy-3-(phenylseleno)butyl]-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester

Chemical Property of 4-[3-ethoxycarbonyl-2-hydroxy-3-(phenylseleno)butyl]-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 4-[3-ethoxycarbonyl-2-hydroxy-3-(phenylseleno)butyl]-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester

There total 1 articles about 4-[3-ethoxycarbonyl-2-hydroxy-3-(phenylseleno)butyl]-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2,2-dimethoxy-4-(2-oxoethyl)cyclohexanecarboxylic acid ethyl ester (1007229-50-6) + Ethyl 2-methyl-2-(phenylseleno)propionate (76893-72-6) → 4-[3-ethoxycarbonyl-2-hydroxy-3-(phenylseleno)butyl]-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester (1007229-51-7)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 2h;

DOI:10.1002/anie.200703022

Reference yield: 98.0%

4-[3-ethoxycarbonyl-2-hydroxy-3-(phenylseleno)butyl]-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester (1007229-51-7) → 4-(3-ethoxycarbonyl-2-hydroxybut-3-enyl)-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester (1007229-52-8)

Guidance literature:

With dihydrogen peroxide; In dichloromethane; at -10 ℃; for 1h;

DOI:10.1002/anie.200703022

upstream raw materials:

2,2-dimethoxy-4-(2-oxoethyl)cyclohexanecarboxylic acid ethyl ester

Ethyl 2-methyl-2-(phenylseleno)propionate

Downstream raw materials:

4-(3-ethoxycarbonyl-2-hydroxybut-3-enyl)-2,2-dimethoxycyclohexanecarboxylic acid ethyl ester