methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate

Base Information

Chemical Name:methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate
CAS No.:441355-04-0
Molecular Formula:C₂₇H₂₄BrNO₅
Molecular Weight:522.395
Hs Code.:

Synonyms:methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate

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Chemical Property of methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate

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Technology Process of methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate

There total 1 articles about methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 220801-66-1
5-bromo-2-hydroxylphenylacetic acid methyl ester

: 250602-53-0
4-{[4-(chloromethyl)phenoxy]methyl}-5-methyl-2-phenyl-1,3-oxazole

: 441355-04-0
methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 0 - 30 ℃; for 15h;

Reference yield: 83.0%

: 441355-04-0
methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate

: 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl]methoxy]benzyloxy]phenyl]acetic acid

Guidance literature:: methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate; With methanol; sodium hydroxide; water; In tetrahydrofuran; at 50 ℃; for 1.5h;

With hydrogenchloride; In tetrahydrofuran; water;

Reference yield: 74.0%

: 441355-04-0
methyl 2-[5-bromo-2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]phenyl]acetate

: 98-80-6
phenylboronic acid

: methyl 2-[2-[4-[(5-methyl-2-phenyl-4-oxazolyl)methoxy]benzyloxy]-5-phenylphenyl]acetate

Guidance literature:: With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In methanol; water; toluene; for 24h; Heating / reflux;