2-Benzyl-3-methylbutanoic acid

Base Information

Chemical Name:2-Benzyl-3-methylbutanoic acid
CAS No.:53483-11-7
Molecular Formula:C₁₂H₁₆O₂
Molecular Weight:192.258
Hs Code.:
European Community (EC) Number:826-512-1

Synonyms:2-benzyl-3-methylbutanoic acid;53483-11-7;2-benzyl-3-methylbutanoicacid;SCHEMBL883357;AKOS010365542;EN300-82667;Z756391626

Suppliers and Price of 2-Benzyl-3-methylbutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Benzyl-3-methylbutanoic acid

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:192.115029749
Heavy Atom Count:14
Complexity:181

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C(CC1=CC=CC=C1)C(=O)O

Technology Process of 2-Benzyl-3-methylbutanoic acid

There total 18 articles about 2-Benzyl-3-methylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 56898-40-9
2-benzyl-3-methyl-butyric acid ethyl ester

: 53483-11-7
2-benzyl-3-methyl-butyric acid

Guidance literature:: With sodium hydroxide; In methanol; at 60 ℃;
DOI:10.1021/acs.orglett.5b01710

Reference yield:

: 53483-11-7
2-benzyl-3-methyl-butyric acid

Guidance literature:: With 1,4-dioxane; hydrogenchloride;
DOI:10.1021/ja01530a066

Reference yield:

: 108-64-5
Ethyl isovalerate

: 53483-11-7
2-benzyl-3-methyl-butyric acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / hexane / 1 h / -78 °C

1.2: -78 - 20 °C

2.1: sodium hydroxide / methanol / 60 °C

With sodium hydroxide; lithium diisopropyl amide; In methanol; hexane;
DOI:10.1021/acs.orglett.5b01710