methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside

Base Information

• Chemical Name: methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside
• CAS No.: 937182-89-3
• Molecular Formula: C₄₅H₅₉N₃O₁₀Si₂
• Molecular Weight: 858.149
• Mol file: 937182-89-3.mol

Synonyms:methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside

Chemical Property of methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside

There total 1 articles about methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methyl O-β-D-galactopyranosyl-(1-4)-2-azido-2-deoxy-β-D-glucopyranoside (91852-14-1) + tert-butylchlorodiphenylsilane (58479-61-1) → methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside (937182-89-3) + methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(3,6-di-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside

Guidance literature:

With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

DOI:10.1021/jo062541y

Reference yield:

Trimethyl orthoacetate (1445-45-0) + methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside (937182-89-3) → C48H63O11N3Si2 (1055041-32-1)

Guidance literature:

With camphor-10-sulfonic acid; In acetonitrile; at 20 ℃;

DOI:10.1021/jo062541y

Reference yield:

Trimethyl orthoacetate (1445-45-0) + methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside (937182-89-3) + acetic anhydride (108-24-7) → C52H67O13N3Si2 (1053652-36-0)

Guidance literature:

Trimethyl orthoacetate; methyl 2-azido-6-O-tert-butyldiphenylsilyl-4-O-(6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-2-deoxy-β-D-glucopyranoside; With camphor-10-sulfonic acid; In acetonitrile; at 20 ℃; for 0.166667h;

acetic anhydride; With pyridine; at 50 ℃; for 3h; Further stages.;

DOI:10.1021/jo062541y

upstream raw materials:

methyl O-β-D-galactopyranosyl-(1-4)-2-azido-2-deoxy-β-D-glucopyranoside

tert-butylchlorodiphenylsilane

Downstream raw materials:

C₄₈H₆₃O₁₁N₃Si₂

C₅₂H₆₇O₁₃N₃Si₂

methyl 3-O-acetyl-2-azido-4-O-(2,4-di-O-acetyl-6-O-tert-butyldiphenylsilyl-β-D-galactopyranosyl)-6-O-tert-butyldiphenylsilyl-2-deoxy-β-D-glucopyranoside