C₂₁H₂₀FN₃O₃S

Base Information

Chemical Name:C₂₁H₂₀FN₃O₃S
CAS No.:1426215-40-8
Molecular Formula:C₂₁H₂₀FN₃O₃S
Molecular Weight:413.473
Hs Code.:

C<sub>21</sub>H<sub>20</sub>FN<sub>3</sub>O<sub>3</sub>S

Synonyms:C₂₁H₂₀FN₃O₃S

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Chemical Property of C₂₁H₂₀FN₃O₃S

Chemical Property:

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Technology Process of C₂₁H₂₀FN₃O₃S

There total 5 articles about C₂₁H₂₀FN₃O₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1426215-41-9
2-chloro-4-(3,4-dihydro-2H-chromen-8-yl)-5-fluoropyrimidine

: 261925-02-4
3-((methylsulfonyl)methyl)aniline

: 1426215-40-8
C₂₁H₂₀FN₃O₃S

Guidance literature:: With potassium phosphate; chloro(2-dicyclohexylphosphino-2',4',6'-tri-iso-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) methyl-tert-butylether; XPhos; In 1-methyl-pyrrolidin-2-one; toluene; at 130 ℃; for 3h; Microwave irradiation; Inert atmosphere;

Reference yield:

: 261924-46-3
1-(methylsulfonylmethyl)-3-nitrobenzene

: 1426215-40-8
C₂₁H₂₀FN₃O₃S

Guidance literature:: Multi-step reaction with 2 steps

1: titanium(III) chloride; hydrogenchloride / water; tetrahydrofuran / 16 h / 20 °C

2: XPhos; chloro(2-dicyclohexylphosphino-2',4',6'-tri-iso-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) methyl-tert-butylether; potassium phosphate / toluene; 1-methyl-pyrrolidin-2-one / 3 h / 130 °C / Microwave irradiation; Inert atmosphere

With hydrogenchloride; potassium phosphate; titanium(III) chloride; chloro(2-dicyclohexylphosphino-2',4',6'-tri-iso-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) methyl-tert-butylether; XPhos; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; water; toluene;

Reference yield:

: 685514-79-8
3,4-dihydro-2H-chromen-8-ylboronic acid

: 1426215-40-8
C₂₁H₂₀FN₃O₃S

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; bis-triphenylphosphine-palladium(II) chloride / 1,2-dimethoxyethane / 16 h / 90 °C / Inert atmosphere

2: XPhos; chloro(2-dicyclohexylphosphino-2',4',6'-tri-iso-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) methyl-tert-butylether; potassium phosphate / toluene; 1-methyl-pyrrolidin-2-one / 3 h / 130 °C / Microwave irradiation; Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; chloro(2-dicyclohexylphosphino-2',4',6'-tri-iso-propyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II) methyl-tert-butylether; potassium carbonate; XPhos; In 1-methyl-pyrrolidin-2-one; 1,2-dimethoxyethane; toluene;