(2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine

Base Information

• Chemical Name: (2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine
• CAS No.: 616215-29-3
• Molecular Formula: C₃₄H₃₅NO₄
• Molecular Weight: 521.656

Synonyms:(2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine

Chemical Property of (2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine

There total 7 articles about (2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R,4R,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-1-chloro-piperidine (616215-28-2) → (2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine (616215-29-3)

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In diethyl ether; Heating;

DOI:10.1002/anie.200351002

Reference yield:

(2S,3R,4R,5S)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)piperidine (76738-52-8) → (2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine (616215-29-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / N-chlorosuccinimide / CH₂Cl₂

2: 1,8-diazabicyclo[5.4.0]undec-7-ene / diethyl ether / Heating

With N-chloro-succinimide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In diethyl ether; dichloromethane;

DOI:10.1002/anie.200351002

Reference yield:

5-azido-2,3,4,6-tetra-O-benzyl-5-deoxy-L-idose (616215-39-5) → (2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine (616215-29-3)

Guidance literature:

With trimethylphosphane; In methanol; toluene; at 0 ℃; for 3h; Inert atmosphere;

DOI:10.1002/ejoc.201200923

upstream raw materials:

(2S,3R,4R,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-1-chloro-piperidine

(2S,3R,4R,5S)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)piperidine

2,3,4,6-tetra-O-benzyl-D-glucitol

(3R,4R,5S)-1,3,4,5-tetrakis(benzyloxy)-6-(tert-butyldiphenylsilyloxy)hexan-2-ol

Downstream raw materials:

(2S,3R,4R,5S,6R)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-6-ethyl-piperidine

5-(adamantan-1-yl-methoxy)pentyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-L-glycero-D-guloheptonamide

5-(adamantan-1-yl-methoxy)pentyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-enimido)-L-glycero-D-idoheptonamide

1,1,3,3-tetramethylbutyl 3,4,5,7-tetra-O-benzyl-2,6-dideoxy-2,6-(pent-4-en-imido)-L-glycero-D-guloheptonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 616215-29-3 (2S,3R,4S,5S)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-2,3,4,5-tetrahydro-pyridine

Send

Send

Metric Ton KG G Pound L ML

Send

Send