1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine

Base Information

Chemical Name:1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine
CAS No.:1004551-67-0
Molecular Formula:C₂₂H₃₁F₃N₂
Molecular Weight:380.497
Hs Code.:

Synonyms:1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine

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Technology Process of 1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine

There total 2 articles about 1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1004541-66-5
(+/-)-2-(4-(dimethylamino)-4-butylcyclohex-1-enyl)-3-methyl-5-trifluoromethyl-1H-indole

: 1004551-65-8
1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine

: 1004551-67-0
1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In methanol; at 20 ℃; for 3h; under 2250.23 Torr; Inert atmosphere;

Reference yield:

: 1002916-43-9
4-butyl-4-(dimethylamino)cyclohexanone

: 1004547-95-8
3-methyl-5-(trifluoromethyl)-1H-indole

: 1004551-65-8
1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine

: 1004551-67-0
1-butyl-N,N-dimethyl-4-(3-methyl-5-(trifluoromethyl)-1H-indol-2-yl)cyclohexanamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 72 h / 20 °C

1.2: 0.17 h

2.1: hydrogen / 5%-palladium/activated carbon / methanol / 3 h / 20 °C / 2250.23 Torr / Inert atmosphere

With trifluorormethanesulfonic acid; hydrogen; 5%-palladium/activated carbon; In methanol; dichloromethane;