ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride

Base Information

Chemical Name:ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride
CAS No.:1567847-46-4
Molecular Formula:C₃₀H₂₈N₂O₄*ClH
Molecular Weight:517.024
Hs Code.:

Synonyms:ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride

Suppliers and Price of ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride

There total 6 articles about ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1567847-44-2
ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate

: 1567847-46-4
ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; dichloromethane;
DOI:10.1016/j.ejmech.2013.12.008

Reference yield:

: 108046-33-9
1-benzyl-1,2,3,4-tetrahydro-2-pyridinone

: 1567847-46-4
ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: scandium tris(trifluoromethanesulfonate) / acetonitrile / 0.08 h / 20 °C / Molecular sieve; Inert atmosphere

1.2: 72 h / 20 °C / Inert atmosphere

1.3: 24 h / Inert atmosphere

2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / chloroform / 20 °C / Inert atmosphere

3.1: zinc diacetate; Triethoxysilane / tetrahydrofuran / 48 h / 65 °C

4.1: hydrogenchloride / dichloromethane; methanol

With hydrogenchloride; Triethoxysilane; zinc diacetate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; methanol; dichloromethane; chloroform; acetonitrile;
DOI:10.1016/j.ejmech.2013.12.008

Reference yield:

: 1571-08-0
methyl 4-formylbenzoate

: 1567847-46-4
ethyl 1-benzyl-1,2,3,4-tetrahydro-5-(4-methoxycarbonylphenyl)benzo[h][1,6]naphthyridine-9-carboxylate hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: scandium tris(trifluoromethanesulfonate) / acetonitrile / 0.08 h / 20 °C / Molecular sieve; Inert atmosphere

1.2: 72 h / 20 °C / Inert atmosphere

1.3: 24 h / Inert atmosphere

2.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / chloroform / 20 °C / Inert atmosphere

3.1: zinc diacetate; Triethoxysilane / tetrahydrofuran / 48 h / 65 °C

4.1: hydrogenchloride / dichloromethane; methanol

With hydrogenchloride; Triethoxysilane; zinc diacetate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; methanol; dichloromethane; chloroform; acetonitrile;
DOI:10.1016/j.ejmech.2013.12.008