N₆-[4-(3-(2-amino-3-(3,4-dichlorobenzoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl)propyloxy)phenyl]adenosine

Base Information

• Chemical Name: N₆-[4-(3-(2-amino-3-(3,4-dichlorobenzoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl)propyloxy)phenyl]adenosine
• CAS No.: 1223426-32-1
• Molecular Formula: C₃₃H₃₃Cl₂N₇O₆S
• Molecular Weight: 726.64

Synonyms:N₆-[4-(3-(2-amino-3-(3,4-dichlorobenzoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl)propyloxy)phenyl]adenosine

Chemical Property of N₆-[4-(3-(2-amino-3-(3,4-dichlorobenzoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl)propyloxy)phenyl]adenosine

Chemical Property:

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Technology Process of N₆-[4-(3-(2-amino-3-(3,4-dichlorobenzoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl)propyloxy)phenyl]adenosine

There total 1 articles about N₆-[4-(3-(2-amino-3-(3,4-dichlorobenzoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl)propyloxy)phenyl]adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

(2-amino-6-[3-(4-aminophenoxy)propyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-3-yl)-(3,4-dichlorophenyl)-methanone (1223426-19-4) + 6-Chloropurine riboside (2004-06-0) → N6-[4-(3-(2-amino-3-(3,4-dichlorobenzoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-6-yl)propyloxy)phenyl]adenosine (1223426-32-1)

Guidance literature:

With triethylamine; In ethanol; at 120 ℃; for 2.5h; Microwave irradiation;

DOI:10.1021/jm901252a

upstream raw materials:

(2-amino-6-[3-(4-aminophenoxy)propyl]-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-3-yl)-(3,4-dichlorophenyl)-methanone

6-Chloropurine riboside

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