Technology Process of 6-chloro-3,3-dimethyl-2-(3-nitro-phenyl)-1,2,3,4-tetrahydro-quinoline
There total 4 articles about 6-chloro-3,3-dimethyl-2-(3-nitro-phenyl)-1,2,3,4-tetrahydro-quinoline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
triethylsilane; trifluoroacetic acid;
at 25 ℃;
for 1h;
With
sodium hydrogencarbonate;
In
water; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: ethanol / 3 h / Reflux
2: water / ytterbium(III) trifluoromethanesulfonate nonohydrate / tetrahydrofuran / 3 h / 25 °C
3: triethylsilane; trifluoroacetic acid / 1 h / 25 °C
With
triethylsilane; water; trifluoroacetic acid;
ytterbium(III) trifluoromethanesulfonate nonohydrate;
In
tetrahydrofuran; ethanol;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: ethanol / 3 h / Reflux
2: water / ytterbium(III) trifluoromethanesulfonate nonohydrate / tetrahydrofuran / 3 h / 25 °C
3: triethylsilane; trifluoroacetic acid / 1 h / 25 °C
With
triethylsilane; water; trifluoroacetic acid;
ytterbium(III) trifluoromethanesulfonate nonohydrate;
In
tetrahydrofuran; ethanol;