Technology Process of 2,4,5-trifluorobenzene magnesium chloride
There total 1 articles about 2,4,5-trifluorobenzene magnesium chloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
tetrahydrofuran;
at -20 - 10 ℃;
for 3h;
Product distribution / selectivity;
- Guidance literature:
-
N,N,N,N,-tetramethylethylenediamine; cobalt(II) bromide;
In
tetrahydrofuran;
at -20 - 0 ℃;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: cobalt(II) bromide / N,N,N,N,-tetramethylethylenediamine / tetrahydrofuran / 0.5 h / 0 °C
1.2: 16 h / -20 - 0 °C
2.1: copper(II) carbonate / triphenylphosphine / water / 24.5 h / 20 °C / Inert atmosphere
3.1: boron trichloride / toluene / 20 °C / Inert atmosphere
3.2: 20 °C / Cooling with ice
With
copper(II) carbonate; boron trichloride; cobalt(II) bromide;
N,N,N,N,-tetramethylethylenediamine; triphenylphosphine;
In
tetrahydrofuran; water; toluene;
