(R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

Base Information

Chemical Name:(R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate
CAS No.:1123888-62-9
Molecular Formula:C₁₇H₂₂FN₃O₆S
Molecular Weight:415.443
Hs Code.:

Synonyms:(R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

Suppliers and Price of (R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

There total 8 articles about (R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₅H₂₀FN₃O₅S*C₂HF₃O₂

: 108-24-7
acetic anhydride

: 1123888-62-9
(R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃;
DOI:10.1016/j.ejmech.2015.10.025

Reference yield:

: 369-34-6
3,4-difluoronitrobenzene

: 1123888-62-9
(R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

Guidance literature:: Multi-step reaction with 8 steps

1: acetonitrile / 90 °C

2: tetrahydrofuran / 20 °C

3: ammonium formate; palladium 10% on activated carbon / methanol; tetrahydrofuran

4: acetone; water / 20 °C

5: n-butyllithium / tetrahydrofuran / -78 °C

6: triethylamine / dichloromethane / 0 - 20 °C

7: dichloromethane / 0 °C

8: triethylamine / dichloromethane / 0 °C

With n-butyllithium; palladium 10% on activated carbon; ammonium formate; triethylamine; In tetrahydrofuran; methanol; dichloromethane; water; acetone; acetonitrile;
DOI:10.1016/j.ejmech.2015.10.025

Reference yield:

: 154590-33-7
1-(2-fluoro-4-nitrophenyl)piperazine

: 1123888-62-9
(R)-(3-(4-(4-acetylpiperazin-1-yl)-3-fluorophenyl)-2-oxooxazolidin-5-yl)methyl methanesulfonate

Guidance literature:: Multi-step reaction with 7 steps

1: tetrahydrofuran / 20 °C

2: ammonium formate; palladium 10% on activated carbon / methanol; tetrahydrofuran

3: acetone; water / 20 °C

4: n-butyllithium / tetrahydrofuran / -78 °C

5: triethylamine / dichloromethane / 0 - 20 °C

6: dichloromethane / 0 °C

7: triethylamine / dichloromethane / 0 °C

With n-butyllithium; palladium 10% on activated carbon; ammonium formate; triethylamine; In tetrahydrofuran; methanol; dichloromethane; water; acetone;
DOI:10.1016/j.ejmech.2015.10.025