Boc-Lys(Z)-Leu-Ala-Arg(NO₂)-OCH₃

Base Information

• Chemical Name: Boc-Lys(Z)-Leu-Ala-Arg(NO₂)-OCH₃
• CAS No.: 1041478-34-5
• Molecular Formula: C₃₅H₅₇N₉O₁₁
• Molecular Weight: 779.891
• Mol file: 1041478-34-5.mol

Synonyms:Boc-Lys(Z)-Leu-Ala-Arg(NO₂)-OCH₃

Chemical Property of Boc-Lys(Z)-Leu-Ala-Arg(NO₂)-OCH₃

Chemical Property:

Purity/Quality:

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Technology Process of Boc-Lys(Z)-Leu-Ala-Arg(NO₂)-OCH₃

There total 1 articles about Boc-Lys(Z)-Leu-Ala-Arg(NO₂)-OCH₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

Boc-Leu-Ala-Arg(NO2)-OCH3 (1041478-26-5) + N-t-butyloxycarbonyl-Nε-benzyloxycarbonyl-lysine pentafluorophenyl ester (50903-59-8) → Boc-Lys(Z)-Leu-Ala-Arg(NO2)-OCH3 (1041478-34-5)

Guidance literature:

Boc-Leu-Ala-Arg(NO₂)-OCH₃; With trifluoroacetic acid;

N-t-butyloxycarbonyl-Nε-benzyloxycarbonyl-lysine pentafluorophenyl ester; With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 4h; pH=9; Further stages.;

DOI:10.1134/S1068162007060027

Reference yield: 92.0%

Boc-Glu(OPfp)-OPfp (1041478-28-7) + Boc-Lys(Z)-Leu-Ala-Arg(NO2)-OCH3 (1041478-34-5) → Boc-Glu[Lys(Z)-Leu-Ala-Arg(NO2)-OCH3]2 (1041478-36-7)

Guidance literature:

Boc-Lys(Z)-Leu-Ala-Arg(NO₂)-OCH₃; With trifluoroacetic acid; for 0.166667h;

Boc-Glu(OPfp)-OPfp; With triethylamine; In acetonitrile; at 20 ℃; for 3h; pH=9; Further stages.;

DOI:10.1134/S1068162007060027

upstream raw materials:

Boc-Leu-Ala-Arg(NO₂)-OCH₃

N-t-butyloxycarbonyl-Nε-benzyloxycarbonyl-lysine pentafluorophenyl ester

Downstream raw materials:

Boc-Glu[Lys(Z)-Leu-Ala-Arg(NO₂)-OCH₃]2

Refernces