ethyl 3-cyano-4-isobutyloxybenzoate

Base Information

• Chemical Name: ethyl 3-cyano-4-isobutyloxybenzoate
• CAS No.: 528607-57-0
• Molecular Formula: C₁₄H₁₇NO₃
• Molecular Weight: 247.294
• Mol file: 528607-57-0.mol

Synonyms:ethyl 3-cyano-4-isobutyloxybenzoate

Chemical Property of ethyl 3-cyano-4-isobutyloxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 3-cyano-4-isobutyloxybenzoate

There total 2 articles about ethyl 3-cyano-4-isobutyloxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

Isobutyl bromide (78-77-3) + ethyl 4-hydroxy-3-cyanobenzoate (34133-59-0) → ethyl 3-cyano-4-isobutyloxybenzoate (528607-57-0)

Guidance literature:

With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 100 ℃; for 10h;

Reference yield:

ethyl 4-nitrobenzoate (99-77-4) → ethyl 3-cyano-4-isobutyloxybenzoate (528607-57-0)

Guidance literature:

Multi-step reaction with 2 steps

1: dimethyl sulfoxide / 4 h / 100 °C

2: potassium carbonate / DMF (N,N-dimethyl-formamide) / 10 h / 100 °C

With potassium carbonate; In DMF (N,N-dimethyl-formamide); dimethyl sulfoxide;

Reference yield: 99.0%

ethyl 3-cyano-4-isobutyloxybenzoate (528607-57-0) → 3-cyano-4-isobutyloxybenzoic acid (528607-60-5)

Guidance literature:

ethyl 3-cyano-4-isobutyloxybenzoate; With sodium hydroxide; In tetrahydrofuran; ethanol; water; at 30 ℃; for 4h;

With hydrogenchloride; In water; pH=1;

upstream raw materials:

Isobutyl bromide

ethyl 4-hydroxy-3-cyanobenzoate

ethyl 4-nitrobenzoate

Downstream raw materials:

3-cyano-4-isobutyloxybenzoic acid

2-(3-Cyano-4-isobutyloxyphenyl)-7-hydroxy-1,3-benzothiazole

2-(3-Cyano-4-isobutyloxyphenyl)-1,3-benzothiazole-7-carboxylic acid

2-(3-Cyano-4-isobutyloxyphenyl)benzimidazole-7-carboxylic acid