N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

Base Information

Chemical Name:N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine
CAS No.:83547-24-4
Molecular Formula:C₂₇H₃₄F₃N₃O₂
Molecular Weight:489.581
Hs Code.:

Synonyms:N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

Suppliers and Price of N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

There total 4 articles about N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 6-Isopropylamino-hexanoic acid [6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-amide

: 83547-24-4
N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

Guidance literature:: With lithium aluminium tetrahydride; aluminium trichloride; In tetrahydrofuran; at -20 - 0 ℃;
DOI:10.1021/jm00356a013

Reference yield:

: 22809-37-6
6-bromohexanoyl chloride

: 83547-24-4
N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / Na₂CO₃ / acetone / 3 h / Heating

2: benzene / Heating

3: 35 percent / AlCl₃, LiAlH₄ / tetrahydrofuran / -20 - 0 °C

With lithium aluminium tetrahydride; aluminium trichloride; sodium carbonate; In tetrahydrofuran; acetone; benzene;
DOI:10.1021/jm00356a013

Reference yield:

: 82333-41-3
8-amino-6-methoxy-4-methyl-5-(3-trifluoromethylphenoxy)quinoline

: 83547-24-4
N-Isopropyl-N'-[6-methoxy-4-methyl-5-(3-trifluoromethyl-phenoxy)-quinolin-8-yl]-hexane-1,6-diamine

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / Na₂CO₃ / acetone / 3 h / Heating

2: benzene / Heating

3: 35 percent / AlCl₃, LiAlH₄ / tetrahydrofuran / -20 - 0 °C

With lithium aluminium tetrahydride; aluminium trichloride; sodium carbonate; In tetrahydrofuran; acetone; benzene;
DOI:10.1021/jm00356a013